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Laropiprant (MK0524)


DP1 抑制剂

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产品目录号: A11483


产品名 目录号 价格 数量
Laropiprant 5mg A11483-5
¥ 1,200.00
Laropiprant 10mg A11483-10
¥ 1,800.00
Laropiprant 25mg A11483-25
¥ 3,800.00
Laropiprant 50mg A11483-50
¥ 6,200.00



Laropiprant is used in combination with niacin to reduce blood cholesterol. Laropiprant acts as a DP1 antagonist, reducing the vasodilation.

Laropiprant (MK0524)




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Chemical Information

目录号 A11483
Mechanism of action Inhibitor
分子量 435.9
化学分子式 C21H19ClFNO4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 571170-77-9
Synonyms Cardaptive, MK 0524, MK-0524
SMILES code CS(=O)(=O)C1=C2C(=CC(=C1)F)C3=C(N2CC4=CC=C(C=C4)Cl)[C@H](CC3)CC(=O)O
化学名称 (3R)-4-[(4-Chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)cyclopent[b]indole-3-acetic acid


Laropiprant is used in combination with niacin to reduce blood cholesterol. Laropiprant acts as a DP1 antagonist, reducing the vasodilation.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.94 mL 114.71 mL 229.41mL
0.5 mM 4.59 mL 22.94 mL 45.88 mL
1 mM 2.29 mL 11.47 mL 22.94 mL
5 mM 0.46 mL 2.29 mL 4.59 mL

*The above data is based on the productmolecular weight 435.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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