LBH589 (Panobinostat)

目录号: A10518

HDAC 抑制剂

LBH589 (Panobinostat)

LBH589 (Panobinostat) Chemical Structure

CAS NO. 404950-80-7

LBH589是异羟肟酸,用作非选择性HDAC抑制剂,HDAC1的IC5o为0.23 nM。

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
50 mg
¥ 1,100.00
100 mg
¥ 1,500.00
200 mg
¥ 2,060.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LBH589是异羟肟酸,用作非选择性HDAC抑制剂,HDAC1的IC5o为0.23 nM。
靶点信息
HDAC (MOLT-4 cells) HDAC (Reh cells)
5 nM20 nM
In vitro (25°C) DMSO 69 mg/mL (197.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Add solvents to the product individually and in order: 2% DMSO+48% PEG 300+2% Tween 80+ddH2O 5
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.62 mL 143.1 mL 286.2 mL
0.5 mM 5.72 mL 28.62 mL 57.24 mL
1 mM 2.86 mL 14.31 mL 28.62 mL
5 mM 0.57 mL 2.86 mL 5.72 mL

*The above data is based on the productmolecular weight 349.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10518
作用机制 Inhibitor (抑制剂)
M. Wt 349.4
Formula C21H23N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 404950-80-7
Synonyms NVP-LBH589, LBH-589
SMILES CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO

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