LCI-699 (Osilodrostat)
目录号: A14013
11β-hydroxylase 抑制剂
Osilodrostat (LCI699) 是一种强效的人类 11β-羟化酶 和 醛固酮合酶 抑制剂,其 IC50 值分别为 2.5 和 0.7 nM。
| Discription | Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 values of 2.5 and 0.7 nM, respectively. | |||||
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| Cell Research |
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| 目录号 | A14013 |
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| 分子式 | C13H10FN3 |
| 分子量 | 227.241 |
| CAS号 | 928134-65-0 |
| SMILES | C1CC2=CN=CN2[C@H]1C3=C(C=C(C=C3)C#N)F |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 43 mg/mL (189.22 mM) | |
| Water | 14 mg/mL (61.6 mM) | ||
| Ethanol | 43 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 44.01 mL | 220.03 mL | 440.06 mL |
| 0.5 mM | 8.8 mL | 44.01 mL | 88.01 mL |
| 1 mM | 4.4 mL | 22 mL | 44.01 mL |
| 5 mM | 0.88 mL | 4.4 mL | 8.8 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2