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LDE225 Diphosphate


Smoothened 抑制剂

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产品目录号: A12774


产品名 目录号 价格 数量
LDE225 Diphosphate 5mg A12774-5
¥ 450.00
LDE225 Diphosphate 10mg A12774-10
¥ 600.00
LDE225 Diphosphate 25mg A12774-25
¥ 850.00
LDE225 Diphosphate 50mg A12774-50
¥ 1,300.00



LDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.

LDE225 Diphosphate




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Chemical Information

目录号 A12774
Mechanism of action Inhibitor
分子量 681.49
化学分子式 C26H32F3N3O11P2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1218778-77-8
Synonyms LDE-225, LDE 225
SMILES code C[C@@H]1CN(C[C@@H](O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F.OP(=O)(O)O.OP(=O)(O)O
化学名称 N/A


LDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.67 mL 73.37 mL 146.74mL
0.5 mM 2.93 mL 14.67 mL 29.35 mL
1 mM 1.47 mL 7.34 mL 14.67 mL
5 mM 0.29 mL 1.47 mL 2.93 mL

*The above data is based on the productmolecular weight 681.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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