LDK378 (Ceritinib) dihydrochloride

目录号: A15142

ALK inhibitor

LDK378 (Ceritinib) dihydrochloride Chemical Structure

CAS NO. 1380575-43-8

LDK378 dihydrochloride is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 700.00
50 mg
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

LDK378 dihydrochloride is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.82 mL 84.09 mL 168.18 mL
0.5 mM 3.36 mL 16.82 mL 33.64 mL
1 mM 1.68 mL 8.41 mL 16.82 mL
5 mM 0.34 mL 1.68 mL 3.36 mL

*The above data is based on the productmolecular weight 594.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15142
MECHANISM OF ACTION Inhibitor
M. Wt 594.6
Formula C28H37Cl2N5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1380575-43-8
Synonyms LDK 378 dihydrochloride, LDK-378 dihydrochloride, Ceritinib dihydrochloride
SMILES CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl.Cl.Cl

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