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Leflunomide

Dehydrogenase 抑制剂

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产品目录号: A10521

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Leflunomide 100mg A10521-100
¥ 500.00
Leflunomide 500mg A10521-500
¥ 1,500.00
Leflunomide 10mM * 1mL in DMSO A10521-10mM-D
¥ 550.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain.

Leflunomide

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Chemical Information

目录号 A10521
Mechanism of action Inhibitor
分子量 270.2
化学分子式 C12H9F3N2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 75706-12-6
Synonyms Arava
SMILES code CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
化学名称 5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide

生物活性

Description
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain.
Targets
Dihydroorotate dehydrogenase

溶解性

Solubility (25°C)* In vitro DMSO 54 mg/mL (199.84 mM
Water <1 mg/mL (<1 mM)
Ethanol 54 mg/mL (199.84 mM
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.01 mL 185.05 mL 370.1mL
0.5 mM 7.4 mL 37.01 mL 74.02 mL
1 mM 3.7 mL 18.5 mL 37.01 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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