Lenalidomide (CC-5013)

目录号: A10522

Ubiquitin ligase inducer

Lenalidomide (CC-5013)

Lenalidomide (CC-5013) Chemical Structure

CAS NO. 191732-72-6

Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.

库存: 现货

规格 价格 数量
50 mg
¥ 500.00
100 mg
¥ 850.00
250 mg
¥ 2,000.00
500 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 620.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.
In vitro (25°C) DMSO 52 mg/mL (200.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.57 mL 192.83 mL 385.65 mL
0.5 mM 7.71 mL 38.57 mL 77.13 mL
1 mM 3.86 mL 19.28 mL 38.57 mL
5 mM 0.77 mL 3.86 mL 7.71 mL

*The above data is based on the productmolecular weight 259.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10522
MECHANISM OF ACTION Inducer
M. Wt 259.3
Formula C13H13N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 191732-72-6
Synonyms CC-5013, Revlimid
SMILES C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N

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