leniolisib (CDZ 173)

Name: leniolisib (CDZ 173)
SKU: A16796
Price: 455 CNY
Rating: 5 (288 reviews)

目录号: A16796

PI3K 抑制剂

Leniolisib（CDZ 173）是一种强效的 PI3Kδ 选择性抑制剂，其生化 IC50 值分别为 PI3Kα 0.244 μM、PI3Kβ 0.424 μM、PI3Kγ 2.23 μM 和 PI3Kδ 0.011 μM。

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Grouped product items
规格	价格	库存
1mg	¥455.00	现货
2mg	¥735.00	现货
5mg	¥1,050.00	现货
10mg	¥1,610.00	现货
25mg	¥3,045.00	现货
50mg	¥4,760.00	现货
100mg	¥6,895.00	现货
*10mM 1mL in DMSO**	¥1,120.00	现货
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Data Sheet

SDS

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生物活性

Discription

Leniolisib(CDZ 173) is a potent PI3Kδ selective inhibitor with biochemical IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16796
分子式	C21H25F3N6O2
分子量	450.46
CAS号	1354690-24-6
SMILES	FC(C1=C(OC)N=CC(N(CCC2=NC=N3)CC2=C3N[C@@H]4CN(C(CC)=O)CC4)=C1)(F)F
其他名称	Leniolisib; CDZ-173; CDZ 173; CDZ173; Leniosilib
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	81 mg/mL (179.81 mM)
	Water	Insoluble
	Ethanol	12 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.2 mL	111 mL	222 mL
0.5 mM	4.44 mL	22.2 mL	44.4 mL
1 mM	2.22 mL	11.1 mL	22.2 mL
5 mM	0.44 mL	2.22 mL	4.44 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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