Lenvatinib mesylate
            目录号: A17567
    
            multi-targeted tyrosine kinase 抑制剂
    
								
							Lenvatinib mesylate(E7080 mesylate),一种口服的多靶点酪氨酸激酶抑制剂,能够抑制 VEGFR1-3、FGFR1-4、PDGFR、KIT 和 RET,显示出强大的抗肿瘤活性。
 
        | Discription | Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities. | ||
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| Targets | 
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| 目录号 | A17567 | 
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| 分子式 | C22H23ClN4O7S | 
| 分子量 | 522.96 | 
| CAS号 | 857890-39-2 | 
| SMILES | O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C2=C1)N.OS(=O)(C)=O | 
| 其他名称 | E7080 mesylate, E 7080, E-7080 | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.  | 
| In vitro | DMSO | 34 mg/mL (65.01 mM) | |
| Ethanol | <1 mg/mL | ||
| *  <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg | 
|---|---|---|---|
| 0.1 mM | 19.12 mL | 95.61 mL | 191.22 mL | 
| 0.5 mM | 3.82 mL | 19.12 mL | 38.24 mL | 
| 1 mM | 1.91 mL | 9.56 mL | 19.12 mL | 
| 5 mM | 0.38 mL | 1.91 mL | 3.82 mL | 
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2