Leptomycin B

Name: Leptomycin B
SKU: A20985
Price: 1435 CNY
Rating: 5 (288 reviews)

目录号: A20985

nuclear export receptor CRM1 抑制剂

Leptomycin B（CI 940；LMB）是一种强效的蛋白质核输出抑制剂。Leptomycin B通过在半胱氨酸残基上进行共价修饰，使CRM1/exportin 1失活。Leptomycin B是一种强效的抗真菌抗生素，能够阻断真核细胞周期。

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Grouped product items
规格	价格	库存
1mg	¥1,435.00	现货
2mg	¥2,450.00	现货
5mg	¥4,515.00	现货
10mg	¥6,440.00	现货
25mg	¥9,695.00	现货
50mg	¥13,055.00	现货
100mg	¥17,675.00	现货
*10mM 1mL in DMSO**	¥2,030.00	现货
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Data Sheet

SDS

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生物活性

Discription

Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20985
分子式	C33H48O6
分子量	540.73
CAS号	87081-35-4
SMILES	O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O
其他名称	CI 940, CI940, CI-940; LMB
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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