Lerociclib (G1T38)

目录号: A18320

CDK inhibitor

Lerociclib (G1T38)

Lerociclib (G1T38) Chemical Structure

CAS NO. 1628256-23-4

Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,500.00
50 mg
¥ 6,500.00
100 mg
¥ 11,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
In vitro DMSO 2 mg/mL (4.21 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.07 mL 105.35 mL 210.7 mL
0.5 mM 4.21 mL 21.07 mL 42.14 mL
1 mM 2.11 mL 10.53 mL 21.07 mL
5 mM 0.42 mL 2.11 mL 4.21 mL

*The above data is based on the productmolecular weight 474.613. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18320
作用机制 Inhibitor (抑制剂)
M. Wt 474.613
Formula C26H34N8O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1628256-23-4
Synonyms G1T-38, G1 T38
SMILES CC(C)N(CC1)CCN1C(C=N2)=CC=C2NC3=NC=C4C(N(C5(CCCCC5)CNC6=O)C6=C4)=N3

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