Lerociclib (G1T38)

Name: Lerociclib (G1T38)
SKU: A18320
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A18320

CDK 抑制剂

Lerociclib (G1T38) 是一种强效且选择性的 CDK4/6 抑制剂，其半抑制浓度（IC50）分别为 CDK4/CyclinD1 1 nM 和 CDK6/CyclinD3 2 nM。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
5mg	¥595.00	现货
10mg	¥1,015.00	现货
25mg	¥2,030.00	现货
50mg	¥3,255.00	现货
100mg	¥5,810.00	现货
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Data Sheet

SDS

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生物活性

Discription

Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.

Targets

Target	Value

产品信息

目录号	A18320
分子式	C26H34N8O
分子量	474.613
CAS号	1628256-23-4
SMILES	CC(C)N(CC1)CCN1C(C=N2)=CC=C2NC3=NC=C4C(N(C5(CCCCC5)CNC6=O)C6=C4)=N3
其他名称	G1T-38, G1 T38
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	2 mg/mL (4.21 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.07 mL	105.35 mL	210.7 mL
0.5 mM	4.21 mL	21.07 mL	42.14 mL
1 mM	2.11 mL	10.53 mL	21.07 mL
5 mM	0.42 mL	2.11 mL	4.21 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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