Lestaurtinib

目录号: A11274

multi-kinase inhibitor

Lestaurtinib

Lestaurtinib Chemical Structure

CAS NO. 111358-88-4

Lestaurtinib (CEP-701;KT-5555) is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases. Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9, 3 and less than 25 nM, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 4,050.00
10 mg
¥ 6,980.00
50 mg
¥ 20,700.00
100 mg
¥ 41,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Lestaurtinib (CEP-701;KT-5555) is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases. Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9, 3 and less than 25 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.76 mL 113.78 mL 227.55 mL
0.5 mM 4.55 mL 22.76 mL 45.51 mL
1 mM 2.28 mL 11.38 mL 22.76 mL
5 mM 0.46 mL 2.28 mL 4.55 mL

*The above data is based on the productmolecular weight 439.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11274
作用机制 Inhibitor (抑制剂)
M. Wt 439.46
Formula C26H21N3O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 111358-88-4
Synonyms CEP-701, CEP701, CEP701; KT-5555, KT5555, KT 5555
SMILES O=C(NC1)C2=C1C3=C(C4=C52)N(C6=C3C=CC=C6)[C@@]([C@@](O)(CO)C7)(C)O[C@H]7N4C8=C5C=CC=C8

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