Letaxaban (TAK-442)

目录号: A12871

factor Xa inhibitor

Letaxaban (TAK-442)

Letaxaban (TAK-442) Chemical Structure

CAS NO. 870262-90-1

Letaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative. TAK-442 inhibited endogenous FXa activity in platelet-poor human [half-maximal inhibitory concentration (IC(50)): 53 nM, TAK-442] and rat (IC(50): 32 nM, TAK-442) plasma.

库存: 现货

规格 价格 数量
5 mg
¥ 3,500.00
10 mg
¥ 6,500.00
25 mg
¥ 12,000.00
50 mg
¥ 20,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Letaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative. TAK-442 inhibited endogenous FXa activity in platelet-poor human [half-maximal inhibitory concentration (IC(50)): 53 nM, TAK-442] and rat (IC(50): 32 nM, TAK-442) plasma.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.83 mL 104.17 mL 208.34 mL
0.5 mM 4.17 mL 20.83 mL 41.67 mL
1 mM 2.08 mL 10.42 mL 20.83 mL
5 mM 0.42 mL 2.08 mL 4.17 mL

*The above data is based on the productmolecular weight 479.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12871
MECHANISM OF ACTION Inhibitor
M. Wt 479.98
Formula C22H26ClN3O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 870262-90-1
Synonyms TAK 442; TAK442
SMILES C1CNC(=O)N(C1)C2CCN(CC2)C(=O)[C@@H](CS(=O)(=O)C3=CC4=C(C=C3)C=C(C=C4)Cl)O

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