Letrozole

目录号: A10523

Aromatase 抑制剂

Letrozole

Letrozole Chemical Structure

CAS NO. 112809-51-5

Letrozole是芳香酶抑制剂。CGS 20267是一种新型的非甾体化合物,在体外(IC50为11.5 nM)和在体内(ED50为1-3μg/ kg p.o.)均能有效抑制芳香化酶。

库存: 现货

规格 价格 数量
10 mg
¥ 200.00
50 mg
¥ 500.00
100 mg
¥ 650.00
10mM * 1mL in DMSO
¥ 650.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Letrozole是芳香酶抑制剂。CGS 20267是一种新型的非甾体化合物,在体外(IC50为11.5 nM)和在体内(ED50为1-3μg/ kg p.o.)均能有效抑制芳香化酶。
靶点信息
Aromatase (Cell-free assay)
0.07 nM-20 nM
In vitro (25°C) DMSO 50 mg/mL (175.25 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC Na 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.05 mL 175.25 mL 350.51 mL
0.5 mM 7.01 mL 35.05 mL 70.1 mL
1 mM 3.51 mL 17.53 mL 35.05 mL
5 mM 0.7 mL 3.51 mL 7.01 mL

*The above data is based on the productmolecular weight 285.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10523
作用机制 Inhibitor (抑制剂)
M. Wt 285.3
Formula C17H11N5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 112809-51-5
Synonyms CGS 20267, Femara, Piroxicam
SMILES C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3

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