Levocetirizine Dihydrochloride
目录号: A17440
Histamine H1 receptor 拮抗剂
左西替利嗪二盐酸盐是西替利嗪的L-异构体和组胺H1受体拮抗剂。它可以增加CD4+ CD25+ T细胞的水平并降低嗜酸性粒细胞的水平,从而减少过敏症状。
Discription | Levocetirizine dihydrochloride is a L-isomer of cetirizine and histamine H1 receptor antagonist. It incrases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms. |
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目录号 | A17440 |
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分子式 | C21H27Cl3N2O3 |
分子量 | 461.8 |
CAS号 | 130018-87-0 |
SMILES | O=C(O)COCCN1CCN([C@@H](C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1.[H]Cl.[H]Cl |
其他名称 | (-)-Cetirizine; UCB 28556; UCB28556; UCB-28556; Xusal; Xyzal; Levocetirizine dihydrochloride |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 91 mg/mL (197.04 mM) | |
Water | 91 mg/mL (197.04 mM) | ||
Ethanol | 7 mg/mL (15.15 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.65 mL | 108.27 mL | 216.54 mL |
0.5 mM | 4.33 mL | 21.65 mL | 43.31 mL |
1 mM | 2.17 mL | 10.83 mL | 21.65 mL |
5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2