Levosimendan
目录号: A11874
Levosimendan 是一种 Ca2+ 敏感剂,通过增强心肌丝对钙的敏感性来增加心肌的收缩力,而不增加细胞内钙浓度。
Discription | Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration. | ||
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目录号 | A11874 |
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分子式 | C14H12N6O |
分子量 | 280.29 |
CAS号 | 141505-33-1 |
SMILES | C[C@@H]1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 48 mg/mL (171.26 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+40%PEG 300+5%Tween80+50%ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.68 mL | 178.39 mL | 356.77 mL |
0.5 mM | 7.14 mL | 35.68 mL | 71.35 mL |
1 mM | 3.57 mL | 17.84 mL | 35.68 mL |
5 mM | 0.71 mL | 3.57 mL | 7.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2