Lexatumumab (HGS-ETR 2) is a human monoclonal antibody of the IgG4?? subtype that functions as an agonist to TRAIL receptor 2 (TRAIL-R2, also known as DR5 or APO-2). This antibody is specifically designed to induce apoptosis in cells exhibiting malignant mesothelioma characteristics. It is primarily utilized in research focused on understanding and treating malignant pleural mesothelioma (MPM), offering significant value in studies aimed at exploring targeted cancer therapies.
Lexatumumab (HGS-ETR 2) is a human monoclonal antibody of the IgG4?? subtype that functions as an agonist to TRAIL receptor 2 (TRAIL-R2, also known as DR5 or APO-2). This antibody is specifically designed to induce apoptosis in cells exhibiting malignant mesothelioma characteristics. It is primarily utilized in research focused on understanding and treating malignant pleural mesothelioma (MPM), offering significant value in studies aimed at exploring targeted cancer therapies.
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