产品详情

生物活性

LF3通过破坏β-catenin和TCF4之间的相互作用（IC50小于2 uM）是典型Wnt信号传导的特异性抑制剂。

溶解度 *

In vitro	DMSO	75 mg/mL (180.05 mM)
	Water	Insoluble
	Ethanol	Warmed: 5 mg/mL (12 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.01 mL	120.03 mL	240.06 mL
0.5 mM	4.8 mL	24.01 mL	48.01 mL
1 mM	2.4 mL	12 mL	24.01 mL
5 mM	0.48 mL	2.4 mL	4.8 mL

*The above data is based on the productmolecular weight 416.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16851
作用机制	Inhibitor (抑制剂)
M. Wt	416.56
Formula	C20H24N4O2S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	664969-54-4
Synonyms	LF 3, LF-3
SMILES	S=C(N1CCN(C/C=C/C2=CC=CC=C2)CC1)NC3=CC=C(S(=O)(N)=O)C=C3