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BTK 抑制剂

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产品目录号: A16261


产品名 目录号 价格 数量
LFM-A13 5mg A16261-5
¥ 400.00
LFM-A13 10mg A16261-10
¥ 700.00
LFM-A13 50mg A16261-50
¥ 2,800.00



LFM-A13 is a potent and selective inhibitor of Btk with IC50 of 17.2 uM; also inhibits PLK3 with IC50 of 7.2 uM.





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Chemical Information

目录号 A16261
Mechanism of action Inhibitor
分子量 360
化学分子式 C11H8Br2N2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 244240-24-2
Synonyms LFM A13
SMILES code C/C(O)=C(/C(O)=N/C1=C(Br)C=CC(Br)=C1)C#N
化学名称 (1Z,2Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enimidic acid


LFM-A13 is a potent and selective inhibitor of Btk with IC50 of 17.2 uM; also inhibits PLK3 with IC50 of 7.2 uM.
2.5 μM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.78 mL 138.89 mL 277.78mL
0.5 mM 5.56 mL 27.78 mL 55.56 mL
1 mM 2.78 mL 13.89 mL 27.78 mL
5 mM 0.56 mL 2.78 mL 5.56 mL

*The above data is based on the productmolecular weight 360. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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