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LGB-321 HCl

Pan-PIM kinase 抑制剂

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产品目录号: A14420


产品名 目录号 价格 数量
LGB-321 HCl 5mg A14420-5
¥ 3,500.00
LGB-321 HCl 10mg A14420-10
¥ 6,000.00
LGB-321 HCl 25mg A14420-25
¥ 12,000.00



LGB-321 HCl is a potent and selective ATP-competitive small molecule inhibitor of PIM kinases (Pan-PIM kinase inhibitor).

LGB-321 HCl




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 LGB-321 HCl 发表的文献 (1)
  • Andrea L. Casillas, .et al. Hypoxia-inducible PIM kinase expression promotes resistance to anti-angiogenic agents, Clin Cancer Res, 2018, Jan 1; 24(1): 169每180 PMID: 29084916

Chemical Information

目录号 A14420
Mechanism of action Inhibitor
分子量 493.91
化学分子式 C23H23ClF3N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1469925-36-7
Synonyms LGB-321, LGB321, LGB 321
SMILES code O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C(N4C[C@@H](N)[C@H](O)[C@@H](C)C4)C=CN=C3.[H]Cl
化学名称 N-(4-((3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide hydrochloride


LGB-321 HCl is a potent and selective ATP-competitive small molecule inhibitor of PIM kinases (Pan-PIM kinase inhibitor).


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.25 mL 101.23 mL 202.47mL
0.5 mM 4.05 mL 20.25 mL 40.49 mL
1 mM 2.02 mL 10.12 mL 20.25 mL
5 mM 0.4 mL 2.02 mL 4.05 mL

*The above data is based on the productmolecular weight 493.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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