LGX 818 (Encorafenib)

目录号: A13226

Selective B-RAF Inhibitor

LGX 818 (Encorafenib)

LGX 818 (Encorafenib) Chemical Structure

CAS NO. 1269440-17-6, 1269440-29-0

LGX818 is an orally available Raf kinase inhibitor with potential antineoplastic activity.

库存: 现货

规格 价格 数量
1 mg
¥ 900.00
5 mg
¥ 3,500.00
10 mg
¥ 5,500.00
25 mg
¥ 10,000.00
10mM * 1mL in DMSO
¥ 4,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

生物活性

LGX818 is an orally available Raf kinase inhibitor with potential antineoplastic activity.
Targets
B-Raf (V600E)
4 nM(EC50)
In vitro DMSO 100 mg/mL (185.18 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (185.18 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.52 mL 92.59 mL 185.18 mL
0.5 mM 3.7 mL 18.52 mL 37.04 mL
1 mM 1.85 mL 9.26 mL 18.52 mL
5 mM 0.37 mL 1.85 mL 3.7 mL

*The above data is based on the productmolecular weight 540.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

产品技术资料

目录号 A13226
MECHANISM OF ACTION Inhibitor
M. Wt 540.01
Formula C22H27ClFN7O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1269440-17-6, 1269440-29-0
Synonyms LGX818, LGX-818
SMILES C[[email protected]@H](CNC1=NC=CC(=N1)C2=CN(N=C2C3=CC(=CC(=C3F)NS(=O)(=O)C)Cl)C(C)C)NC(=O)OC

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