LGX 818 (Encorafenib)

Name: LGX 818 (Encorafenib)
SKU: A13226
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A13226

Selective B-RAF 抑制剂

1 篇发表文献

LGX818 是一种口服可用的 Raf 激酶抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
5mg	¥560.00	现货
10mg	¥805.00	现货
25mg	¥1,295.00	现货
50mg	¥2,555.00	现货
100mg	¥4,760.00	现货
*10mM 1mL in DMSO**	¥770.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用LGX 818 (Encorafenib)发表的1篇文献

Seidel D, .et al. , Biosens Bioelectron, 2019, Jan 1;123:185-194 PMID: 30201332

生物活性

Discription

LGX818 is an orally available Raf kinase inhibitor with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A13226
分子式	C22H27ClFN7O4S
分子量	540.01
CAS号	1269440-17-6, 1269440-29-0 (R-isomer)
SMILES	C[C@@H](CNC1=NC=CC(=N1)C2=CN(N=C2C3=CC(=CC(=C3F)NS(=O)(=O)C)Cl)C(C)C)NC(=O)OC
其他名称	LGX818, LGX-818
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	93 mg/mL (172.22 mM)
	Water	Insoluble
	Ethanol	93 mg/mL (172.22 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.52 mL	92.59 mL	185.18 mL
0.5 mM	3.7 mL	18.52 mL	37.04 mL
1 mM	1.85 mL	9.26 mL	18.52 mL
5 mM	0.37 mL	1.85 mL	3.7 mL

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