Lifastuzumab is a humanized monoclonal antibody of the IgG1 subtype, targeting the sodium-dependent phosphate transport protein 2b (NaPi2b). This antibody can be conjugated to monomethyl auristatin E (MMAE) via an ADC linker, creating the antibody-drug conjugate lifastuzumab vedotin (DNIB0600A). The resulting conjugate exhibits potent anticancer activity, making it a valuable tool for targeted cancer therapy research.
Lifastuzumab is a humanized monoclonal antibody of the IgG1 subtype, targeting the sodium-dependent phosphate transport protein 2b (NaPi2b). This antibody can be conjugated to monomethyl auristatin E (MMAE) via an ADC linker, creating the antibody-drug conjugate lifastuzumab vedotin (DNIB0600A). The resulting conjugate exhibits potent anticancer activity, making it a valuable tool for targeted cancer therapy research.
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