主页 /
Lifitegrast

Lifitegrast

Name: Lifitegrast
SKU: A17299

目录号: A17299

LFA-1 antagonist

Lifitegrast Chemical Structure

CAS NO. 1025967-78-5

Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.

库存：现货

规格	价格	数量
10 mg	￥ 590.00
50 mg	￥ 1,770.00
100 mg	￥ 2,950.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.

溶解度 *

In vitro	DMSO	98 mg/mL (159.22 mM)
	Water	Insoluble
	Ethanol	20 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.25 mL	81.24 mL	162.48 mL
0.5 mM	3.25 mL	16.25 mL	32.5 mL
1 mM	1.62 mL	8.12 mL	16.25 mL
5 mM	0.32 mL	1.62 mL	3.25 mL

*The above data is based on the productmolecular weight 615.478. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17299
作用机制	Antagonist (拮抗剂)
M. Wt	615.478
Formula	C29H24Cl2N2O7S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1025967-78-5
Synonyms	SAR-1118; SAR 1118; SAR1118; Lifitegrast, brand name: Xiidra.
SMILES	O=C(O)[C@@H](NC(C1=C(Cl)C2=C(CN(C(C3=CC=C4C=COC4=C3)=O)CC2)C=C1Cl)=O)CC5=CC=CC(S(=O)(C)=O)=C5