Linagliptin (BI-1356)

Name: Linagliptin (BI-1356)
SKU: A11224
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A11224

DPP-4 抑制剂

1 篇发表文献

Linagliptin 是一种 DPP-4 抑制剂，它能抑制分解肠促胰岛素激素，如胰高血糖素样肽-1（GLP-1）和葡萄糖依赖性胰岛素促进多肽（GIP）的酶。

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Grouped product items
规格	价格	库存
50mg	¥210.00	现货
100mg	¥315.00	现货
500mg	¥595.00	现货
1g	¥1,120.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
更大包装	更多折扣

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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Linagliptin (BI-1356)发表的1篇文献

Fen Zhuge, .et al. , Exp Neurol, 2024, Mar:373:114689 PMID: 38199510

生物活性

Discription

Linagliptin is a DPP-4 inhibitor, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11224
分子式	C25H28N8O2
分子量	472.5
CAS号	668270-12-0
SMILES	CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
其他名称	BI-1356,Tradjenta,Trajenta
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	16 mg/mL (33.85 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (2.11 mM)
In vivo	0.5% hydroxyethyl cellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.16 mL	105.82 mL	211.64 mL
0.5 mM	4.23 mL	21.16 mL	42.33 mL
1 mM	2.12 mL	10.58 mL	21.16 mL
5 mM	0.42 mL	2.12 mL	4.23 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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