Livmoniplimab (ABBV-151) is a monoclonal antibody targeting the GARP/TGF-??1 complex, effectively inhibiting the release of active transforming growth factor-beta 1 (TGF-??1). Demonstrating significant anti-tumor activity in murine models of colon cancer, Livmoniplimab is primarily utilized in research focused on locally advanced or metastatic solid tumors. This antibody serves as a crucial tool in the investigation of TGF-??1's role in tumor microenvironments and cancer progression, offering potential insights into therapeutic strategies for solid tumors.
Livmoniplimab (ABBV-151) is a monoclonal antibody targeting the GARP/TGF-??1 complex, effectively inhibiting the release of active transforming growth factor-beta 1 (TGF-??1). Demonstrating significant anti-tumor activity in murine models of colon cancer, Livmoniplimab is primarily utilized in research focused on locally advanced or metastatic solid tumors. This antibody serves as a crucial tool in the investigation of TGF-??1's role in tumor microenvironments and cancer progression, offering potential insights into therapeutic strategies for solid tumors.
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