LJH685
目录号: A14372
pan-RSK 抑制剂
LJH685 是一种强效、特异性和选择性的 RSK 抑制剂，能够抑制 RSK1、RSK2 和 RSK3 的生化活性，IC50 值为 4 至 13 nM。
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生物活性
| Discription | LJH685 is a potent , specific and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50 of 4 to 13 nM. | |||||
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产品信息
| 目录号 | A14372 |
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| 分子式 | C22H21F2N3O |
| 分子量 | 381.42 |
| CAS号 | 1627710-50-2 |
| SMILES | CN(CC1)CCN1C(C=C2)=CC=C2C3=CC=NC=C3C4=CC(F)=C(O)C(F)=C4 |
| 其他名称 | LJH 685, LJH-685 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 66 mg/mL (173.03 mM) | |
| Water | Insoluble | ||
| Ethanol | 17 mg/mL (44.57 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.22 mL | 131.09 mL | 262.18 mL |
| 0.5 mM | 5.24 mL | 26.22 mL | 52.44 mL |
| 1 mM | 2.62 mL | 13.11 mL | 26.22 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.24 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1627710-50-2 | 1627710-50-2 供应商 | 1627710-50-2 花费 | 1627710-50-2 生产商 | 订购 1627710-50-2 | 1627710-50-2 代理商