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LJI308

RSK 抑制剂

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产品目录号: A14373

库存状态:中国现货中国现货

产品名 目录号 价格 数量
LJI308 5mg A14373-5
¥ 1,200.00
LJI308 10mg A14373-10
¥ 2,000.00
LJI308 25mg A14373-25
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

LJI308 is a new and potent pan-RSK inhibitor, with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.

LJI308

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Chemical Information

目录号 A14373
Mechanism of action Inhibitor
分子量 368.38
化学分子式 C21H18F2N2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1627709-94-7
Synonyms LJI 308, LJI-30
SMILES code OC1=C(F)C=C(C2=C(C3=CC=C(N4CCOCC4)C=C3)C=CN=C2)C=C1F
化学名称 2,6-difluoro-4-(4-(4-morpholinophenyl)pyridin-3-yl)phenol

生物活性

Description
LJI308 is a new and potent pan-RSK inhibitor, with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
Targets
RSK2 RSK1 RSK3
4 nM6 nM13 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.15 mL 135.73 mL 271.46mL
0.5 mM 5.43 mL 27.15 mL 54.29 mL
1 mM 2.71 mL 13.57 mL 27.15 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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