Locostatin is a potent inhibitor of Raf kinase inhibitor protein (RKIP), which disrupts its interactions with Raf-1 kinase and G protein-coupled receptor kinase 2. This compound demonstrates significant inhibition of cell proliferation and migration, making it a valuable tool for studying cellular signaling pathways. Additionally, Locostatin is useful for synthesizing chemical probes targeting PEBP proteins and has shown to exacerbate thioacetamide-induced acute liver failure in murine models, thereby providing insights into liver pathology.
Locostatin is a potent inhibitor of Raf kinase inhibitor protein (RKIP), which disrupts its interactions with Raf-1 kinase and G protein-coupled receptor kinase 2. This compound demonstrates significant inhibition of cell proliferation and migration, making it a valuable tool for studying cellular signaling pathways. Additionally, Locostatin is useful for synthesizing chemical probes targeting PEBP proteins and has shown to exacerbate thioacetamide-induced acute liver failure in murine models, thereby providing insights into liver pathology.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
