Lonafarnib (SCH66336)

Name: Lonafarnib (SCH66336)
SKU: A12328
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A12328

FPTase 抑制剂

1 篇发表文献

Lonafarnib（SCH 66336）是一种选择性的FPTase抑制剂，针对H-ras、K-ras-4B和N-ras，其IC50分别为1.9 nM、5.2 nM和2.8 nM。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥595.00	现货
10mg	¥1,015.00	现货
25mg	¥1,925.00	现货
50mg	¥3,430.00	现货
100mg	¥4,795.00	现货
*10mM 1mL in DMSO**	¥1,218.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Lonafarnib (SCH66336)发表的1篇文献

Stella Liong, .et al. , Mediators Inflamm, 2018, 2018: 3645386 PMID: 30402038

生物活性

Discription

Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12328
分子式	C27H31Br2ClN4O2
分子量	638.82
CAS号	193275-84-2
SMILES	C1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N
其他名称	Sarasar, SCH 66336, SCH66336, SCH-66336
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	116 mg/mL (181.58 mM)
	Water	Insoluble
	Ethanol	116 mg/mL (181.58 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.65 mL	78.27 mL	156.54 mL
0.5 mM	3.13 mL	15.65 mL	31.31 mL
1 mM	1.57 mL	7.83 mL	15.65 mL
5 mM	0.31 mL	1.57 mL	3.13 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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