Loratadine

目录号: A10538

Loratadine

Loratadine Chemical Structure

CAS NO. 79794-75-5

Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

库存: 现货

规格 价格 数量
10 mg
¥ 450.00
25 mg
¥ 800.00
50 mg
¥ 1,200.00
100 mg
¥ 1,900.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
Targets
H1 receptor B(0)AT2
N/A4 μM
In vitro DMSO 17 mg/mL (44.4 mM)
Water <1 mg/mL (<1 mM)
Ethanol 77 mg/mL (201.1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.76 mL 261.51 mL
0.5 mM 5.23 mL 26.15 mL 52.3 mL
1 mM 2.62 mL 13.08 mL 26.15 mL
5 mM 0.52 mL 2.62 mL 5.23 mL

*The above data is based on the productmolecular weight 382.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10538
MECHANISM OF ACTION N/A
M. Wt 382.39
Formula C22H23ClN2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 79794-75-5
Synonyms Alavert, Claritin
SMILES CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

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