LOXO-101 sulfate

目录号: A16239

TRK inhibitor

LOXO-101 sulfate Chemical Structure

CAS NO. 1223405-08-0

LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.

库存: 现货

规格 价格 数量
5 mg
¥ 550.00
10 mg
¥ 900.00
50 mg
¥ 1,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.
Targets
TRK
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.99 mL 94.96 mL 189.93 mL
0.5 mM 3.8 mL 18.99 mL 37.99 mL
1 mM 1.9 mL 9.5 mL 18.99 mL
5 mM 0.38 mL 1.9 mL 3.8 mL

*The above data is based on the productmolecular weight 526.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16239
MECHANISM OF ACTION Inhibitor
M. Wt 526.51
Formula C21H24F2N6O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1223405-08-0
Synonyms LOXO101 sulfate, LOXO 101 sulfate
SMILES C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O

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