LOXO-101 sulfate

Name: LOXO-101 sulfate
SKU: A16239
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A16239

TRK 抑制剂

LOXO-101 是一种小分子化合物，旨在阻断 TRK 家族受体的 ATP 结合位点，对 TRKA、TRKB 和 TRKC 激酶具有 2 到 20 nM 的细胞活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥875.00	现货
50mg	¥1,120.00	现货
100mg	¥1,960.00	现货
500mg	¥4,795.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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Data Sheet

SDS

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生物活性

Discription

LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16239
分子式	C21H24F2N6O6S
分子量	526.51
CAS号	1223405-08-0
SMILES	C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O
其他名称	LOXO101 sulfate, LOXO 101 sulfate
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	88 mg/mL (167.13 mM)
	Water	Insoluble
	Ethanol	88 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.99 mL	94.96 mL	189.93 mL
0.5 mM	3.8 mL	18.99 mL	37.99 mL
1 mM	1.9 mL	9.5 mL	18.99 mL
5 mM	0.38 mL	1.9 mL	3.8 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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