LRRK2-IN-1
目录号: A11477
LRRK2 抑制剂
LRRK2-IN-1 抑制 G2019S 突变型和野生型 LRRK2 激酶活性，其 IC50 值分别为 6 nM 和 13 nM。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | LRRK2-IN-1 inhibits both G2019S mutant and wild-type LRRK2 kinase activity with IC50 values of 6 and 13 nM respectively. | |||||
|---|---|---|---|---|---|---|
| Targets |
|
|||||
| Cell Research |
|
产品信息
| 目录号 | A11477 |
|---|---|
| 分子式 | C31H38N8O3 |
| 分子量 | 570.09 |
| CAS号 | 1234480-84-2 |
| SMILES | CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 97 mg/mL (169.96 mM) | |
| Water | Insoluble | ||
| Ethanol | 97 mg/mL (169.96 mM) | ||
| In vivo | Captisol | 16 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.54 mL | 87.71 mL | 175.41 mL |
| 0.5 mM | 3.51 mL | 17.54 mL | 35.08 mL |
| 1 mM | 1.75 mL | 8.77 mL | 17.54 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 LRRK2-IN-1 | LRRK2-IN-1 供应商 | LRRK2-IN-1 花费 | LRRK2-IN-1 生产商 | 订购 LRRK2-IN-1 | LRRK2-IN-1 代理商
| 购买 1234480-84-2 | 1234480-84-2 供应商 | 1234480-84-2 花费 | 1234480-84-2 生产商 | 订购 1234480-84-2 | 1234480-84-2 代理商