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LSN 3213128

LSN 3213128

Name: LSN 3213128
SKU: A19472

目录号: A19472

AICARFT inhibitor

LSN 3213128 Chemical Structure

CAS NO. 1941211-99-9

LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.42 mL	122.11 mL	244.22 mL
0.5 mM	4.88 mL	24.42 mL	48.84 mL
1 mM	2.44 mL	12.21 mL	24.42 mL
5 mM	0.49 mL	2.44 mL	4.88 mL

*The above data is based on the productmolecular weight 409.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19472
作用机制	Inhibitor (抑制剂)
M. Wt	409.46
Formula	C17H16FN3O4S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1941211-99-9
Synonyms	LSN3213128, LSN-3213128
SMILES	O=C1NC=CC2=C1C=C(NS(=O)(C3=CC=C(N4CC[C@@H](O)C4)S3)=O)C(F)=C2