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LuAE58054是一种有效且选择性的5-HT6受体拮抗剂，Ki 为 0.83 nM。由伦德贝克（Lundbeck）开发，作为增强疗法，用于治疗与阿尔茨海默氏病和精神分裂症相关的认知缺陷。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23 mL | 114.99 mL | 229.97 mL |
| 0.5 mM | 4.6 mL | 23 mL | 45.99 mL |
| 1 mM | 2.3 mL | 11.5 mL | 23 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
*The above data is based on the productmolecular weight 434.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14356 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 434.83 |
| Formula | C20H20ClF5N2O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 467458-02-2 |
| Synonyms | Lu AE58054, Lu AE-58054, Lu AE 58054 |
| SMILES | C1=CC(=CC(=C1)OCC(C(F)F)(F)F)CNCCC2=CNC3=C2C=CC(=C3)F.Cl |
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