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Lusutrombopag

Lusutrombopag

Name: Lusutrombopag
SKU: A18089

目录号: A18089

thrombopoietin (TPO) receptor agonist

Lusutrombopag Chemical Structure

CAS NO. 1110766-97-6

Lusutrombopag, also known as S-888711, is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.

库存：现货

规格	价格	数量
2 mg	￥ 1,200.00
5 mg	￥ 2,200.00
10 mg	￥ 3,800.00
50 mg	￥ 12,000.00

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生物活性

溶解度 *

In vitro	DMSO	95 mg/mL (160.59 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.91 mL	84.53 mL	169.05 mL
0.5 mM	3.38 mL	16.91 mL	33.81 mL
1 mM	1.69 mL	8.45 mL	16.91 mL
5 mM	0.34 mL	1.69 mL	3.38 mL

*The above data is based on the productmolecular weight 591.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18089
作用机制	Agonist (激动剂)
M. Wt	591.54
Formula	C29H32Cl2N2O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1110766-97-6
Synonyms	S-888711; S 888711; S888711; Lusutrombopag, brand name: Mulpleta.
SMILES	O=C(O)/C(C)=C/C1=C(Cl)C=C(C(NC2=NC(C3=CC=CC([C@@H](OCCCCCC)C)=C3OC)=CS2)=O)C=C1Cl