Lusutrombopag
目录号: A18089
thrombopoietin (TPO) receptor 激动剂
Lusutrombopag,也被称为 S-888711,是一种口服生物可利用的小分子血小板生成素(TPO)受体激动剂,由Shionogi公司开发,用于慢性肝病(CLD)患者在择期侵入性手术前治疗血小板减少症。
| Discription | Lusutrombopag, also known as S-888711, is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. | |||||
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| Cell Research |
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| 目录号 | A18089 |
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| 分子式 | C29H32Cl2N2O5S |
| 分子量 | 591.54 |
| CAS号 | 1110766-97-6 |
| SMILES | O=C(O)/C(C)=C/C1=C(Cl)C=C(C(NC2=NC(C3=CC=CC([C@@H](OCCCCCC)C)=C3OC)=CS2)=O)C=C1Cl |
| 其他名称 | S-888711; S 888711; S888711; Lusutrombopag, brand name: Mulpleta. |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 95 mg/mL (160.59 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.91 mL | 84.53 mL | 169.05 mL |
| 0.5 mM | 3.38 mL | 16.91 mL | 33.81 mL |
| 1 mM | 1.69 mL | 8.45 mL | 16.91 mL |
| 5 mM | 0.34 mL | 1.69 mL | 3.38 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2