Lusvertikimab (OSE-127) is a humanized monoclonal antibody that targets the interleukin-7 receptor (IL7R). This antibody uniquely binds to IL7R without being internalized by the target cells, effectively inhibiting IL7R heterodimerization and the subsequent downstream signaling pathways. Lusvertikimab demonstrates anti-leukemic properties and holds significant potential for research in B cell precursor acute lymphoblastic leukemia (BCP-ALL), making it a valuable tool for studies aimed at understanding and potentially treating this condition.
Lusvertikimab (OSE-127) is a humanized monoclonal antibody that targets the interleukin-7 receptor (IL7R). This antibody uniquely binds to IL7R without being internalized by the target cells, effectively inhibiting IL7R heterodimerization and the subsequent downstream signaling pathways. Lusvertikimab demonstrates anti-leukemic properties and holds significant potential for research in B cell precursor acute lymphoblastic leukemia (BCP-ALL), making it a valuable tool for studies aimed at understanding and potentially treating this condition.
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