Lutikizumab (ABT-981) is a dual variable domain immunoglobulin designed to specifically target and inhibit both interleukin-1 alpha (IL-1??) and interleukin-1 beta (IL-1??). This monoclonal antibody functions by binding to these cytokines, effectively neutralizing their activity and mitigating their pro-inflammatory effects. Lutikizumab is primarily utilized in research focused on understanding and treating osteoarthritis, providing a valuable tool for investigating the role of IL-1 in inflammatory processes associated with this degenerative disease.
Lutikizumab (ABT-981) is a dual variable domain immunoglobulin designed to specifically target and inhibit both interleukin-1 alpha (IL-1??) and interleukin-1 beta (IL-1??). This monoclonal antibody functions by binding to these cytokines, effectively neutralizing their activity and mitigating their pro-inflammatory effects. Lutikizumab is primarily utilized in research focused on understanding and treating osteoarthritis, providing a valuable tool for investigating the role of IL-1 in inflammatory processes associated with this degenerative disease.
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