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LX 1606 (Telotristat)


Serotonin synthesis 抑制剂

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产品目录号: A11785


产品名 目录号 价格 数量
LX 1606 5mg A11785-5
¥ 1,200.00
LX 1606 10mg A11785-10
¥ 2,200.00
LX 1606 50mg A11785-50
¥ 6,800.00
LX 1606 100mg A11785-100
¥ 10,500.00



LX 1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.

LX 1606 (Telotristat)




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Chemical Information

目录号 A11785
Mechanism of action Inhibitor
分子量 575.0
化学分子式 C27H26ClF3N6O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1033805-22-9
Synonyms LX1606
SMILES code CCOC(=O)[C@H](CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)O[C@H](C3=C(C=C(C=C3)Cl)N4C=CC(=N4)C)C(F)(F)F)N
化学名称 (2S)-2-Amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid ethyl ester


LX 1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.39 mL 86.96 mL 173.91mL
0.5 mM 3.48 mL 17.39 mL 34.78 mL
1 mM 1.74 mL 8.7 mL 17.39 mL
5 mM 0.35 mL 1.74 mL 3.48 mL

*The above data is based on the productmolecular weight 575.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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