LXH254

目录号: A16841

pan-RAF 抑制剂

LXH254

LXH254 Chemical Structure

CAS NO. 1800398-38-2

LXH254是II型ATP竞争性抑制剂,可在皮摩尔浓度下抑制B/C RAF激酶活性,对456种人类激酶和基于细胞的测定具有高度选择性。

库存: 现货

规格 价格 数量
2 mg
¥ 1,400.00
5 mg
¥ 2,500.00
10 mg
¥ 3,500.00
50 mg
¥ 12,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LXH254是II型ATP竞争性抑制剂,可在皮摩尔浓度下抑制B/C RAF激酶活性,对456种人类激酶和基于细胞的测定具有高度选择性。
In vitro DMSO 85 mg/mL (169.15 mM)
Water Insoluble
Ethanol 29 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.9 mL 99.5 mL 199.01 mL
0.5 mM 3.98 mL 19.9 mL 39.8 mL
1 mM 1.99 mL 9.95 mL 19.9 mL
5 mM 0.4 mL 1.99 mL 3.98 mL

*The above data is based on the productmolecular weight 502.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16841
作用机制 Inhibitor (抑制剂)
M. Wt 502.49
Formula C25H25F3N4O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1800398-38-2
Synonyms LXH 254, LXH-254
SMILES O=C(C1=CC(C(F)(F)F)=NC=C1)NC2=CC=C(C)C(C3=CC(OCCO)=NC(N4CCOCC4)=C3)=C2

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