LY 3200882

Name: LY 3200882
SKU: A16816
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A16816

TGFβRI 抑制剂

LY 3200882 是一种强效的、高度选择性的 TGF-β 受体类型 1 (TGFβRI) 抑制剂。它在体外的肿瘤和免疫细胞中以及体内的皮下肿瘤中，都能强效抑制 TGFβ 介导的 SMAD 磷酸化，并且这种抑制作用是剂量依赖性的。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥385.00	现货
5mg	¥560.00	现货
10mg	¥980.00	现货
25mg	¥1,960.00	现货
50mg	¥3,150.00	现货
100mg	¥4,760.00	现货
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Data Sheet

SDS

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生物活性

Discription	LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.

产品信息

目录号	A16816
分子式	C24H29N5O3
分子量	435.52
CAS号	1898283-02-7
SMILES	CC(O)(C)C1=NC=CC(NC2=NC=CC(OC3=CN(C4CC4)N=C3C5CCOCC5)=C2)=C1
其他名称	LY-3200882, LY3200882
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	79 mg/mL (181.39 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.96 mL	114.81 mL	229.61 mL
0.5 mM	4.59 mL	22.96 mL	45.92 mL
1 mM	2.3 mL	11.48 mL	22.96 mL
5 mM	0.46 mL	2.3 mL	4.59 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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