LY-411575

Name: LY-411575
SKU: A11176
Price: 210 CNY
Rating: 5 (6 reviews)

目录号: A11176

Gamma secretase 抑制剂

6 篇发表文献

LY-411575 是一种选择性的、细胞渗透性的、小分子 伽玛分泌酶抑制剂。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥700.00	现货
25mg	¥1,505.00	现货
50mg	¥2,975.00	现货
100mg	¥4,410.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用LY-411575发表的6篇文献

Haiwen Yu, .et al. , Immunol Invest, 2023, Feb;52(2):241-255 PMID: 36562737

Wojciech J Szlachcic, .et al. , iScience, 2022, Jul 15;25(7) PMID: 35756892

Zhang ZH, .et al. , APMIS, 2019, Jul 5 PMID: 31274210

Bo Pang, .et al. , Biosci Rep, 2018, Dec 21; 38(6): BSR20181922 PMID: 30473538

Shuo Li, .et al. , Int Immunopharmacol, 2018, Oct;63:129-136 PMID: 30086535

Jiang BC, .et al. , Viral Immunol, 2017, Sep;30(7):522-532 PMID: 28410452

生物活性

Discription

LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11176
分子式	C26H23F2N3O4
分子量	479.48
CAS号	209984-57-6
SMILES	C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C4=CC(=CC(=C4)F)F)O
其他名称	LY411575
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	94 mg/mL (196.04 mM)
	Water	Insoluble
	Ethanol	13 mg/mL (27.11 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.86 mL	104.28 mL	208.56 mL
0.5 mM	4.17 mL	20.86 mL	41.71 mL
1 mM	2.09 mL	10.43 mL	20.86 mL
5 mM	0.42 mL	2.09 mL	4.17 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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