LY2109761

Name: LY2109761
SKU: A11133
Price: 210 CNY
Rating: 5 (5 reviews)

目录号: A11133

TβRI/II kinase 抑制剂

5 篇发表文献

LY2109761，一种新型的转化生长因子β受体I型和II型双重抑制剂，作为抑制胰腺癌转移的治疗方法。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥735.00	现货
25mg	¥1,330.00	现货
50mg	¥2,205.00	现货
100mg	¥3,605.00	现货
200mg	¥5,320.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用LY2109761发表的5篇文献

Yimei Wei, .et al. , Int J Rheum Dis, 2024, May;27(5):e15164 PMID: 38706209

Yan Yang, .et al. , J Thorac Dis, 2024, Feb 29;16(2):1128-1140 PMID: 38505034

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Uto T, .et al. , J Allergy Clin Immunol, 2018, Jun;141(6):2156-2167.e9 PMID: 29477579

Jared M. Fischer, .et al. , Proc Natl Acad Sci U S A, 2016, Oct 25; 113(43): 12192-12197 PMID: 27791005

生物活性

Discription

LY2109761, a novel transforming growth factor β receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11133
分子式	C26H27N5O2
分子量	441.5
CAS号	700874-71-1
SMILES	C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6
其他名称	LY-2109761
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	2 mg/mL (4.52 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80 (suspensions)	15 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.65 mL	113.25 mL	226.5 mL
0.5 mM	4.53 mL	22.65 mL	45.3 mL
1 mM	2.27 mL	11.33 mL	22.65 mL
5 mM	0.45 mL	2.27 mL	4.53 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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