Galunisertib (LY2157299)

Name: Galunisertib (LY2157299)
SKU: A11017
Price: 175 CNY
Rating: 5 (4 reviews)

目录号: A11017

TGF-βR 抑制剂

4 篇发表文献

LY2157299 是一种口服活性的转化生长因子β受体（TGF-βR）激酶抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥455.00	现货
50mg	¥665.00	现货
100mg	¥1,225.00	现货
200mg	¥2,030.00	现货
500mg	¥3,395.00	现货
1g	¥5,040.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Galunisertib (LY2157299)发表的4篇文献

Yuri Nagaoka, .et al. , Arch Biochem Biophys, 2024, Jan:751:109824 PMID: 37984759

Eunji Jang, .et al. , Exp Mol Med, 2023, May;55(5):974-986 PMID: 37121972

Satoshi Endo, .et al. , Nutr Res, 2019, 4 November

Oguri G, .et al. , Am J Physiol Heart Circ Physiol., 2014, 307(9):H1339-52 PMID: 25172898

生物活性

Discription

LY2157299 is an orally active transforming growth factor beta receptor (TGF-βR) kinase inhibitor.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11017
分子式	C22H19N5O
分子量	369.4
CAS号	700874-72-2
SMILES	CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
其他名称	LY-2157299
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	66 mg/mL (178.65 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1%CMC-Na	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.07 mL	135.35 mL	270.71 mL
0.5 mM	5.41 mL	27.07 mL	54.14 mL
1 mM	2.71 mL	13.54 mL	27.07 mL
5 mM	0.54 mL	2.71 mL	5.41 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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