LY2228820 (Ralimetinib)

目录号: A10545

p38 MAPK inhibitor

LY2228820 (Ralimetinib)

LY2228820 (Ralimetinib) Chemical Structure

CAS NO. 862507-23-1

LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 5,800.00
100 mg
¥ 9,500.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity.
Targets
p38α (Cell-free assay)
7 nM
In vitro (25°C) DMSO 35 mg/mL (57.12 mM)
Water 123 mg/mL (200.73 mM)
Ethanol 3 mg/mL (4.89 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.32 mL 81.61 mL 163.21 mL
0.5 mM 3.26 mL 16.32 mL 32.64 mL
1 mM 1.63 mL 8.16 mL 16.32 mL
5 mM 0.33 mL 1.63 mL 3.26 mL

*The above data is based on the productmolecular weight 612.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10545
MECHANISM OF ACTION Inhibitor
M. Wt 612.7
Formula C24H29FN6.2CH4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 862507-23-1
Synonyms LY-2228820
SMILES CC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O

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