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LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.7 mL | 118.51 mL | 237.02 mL |
| 0.5 mM | 4.74 mL | 23.7 mL | 47.4 mL |
| 1 mM | 2.37 mL | 11.85 mL | 23.7 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
*The above data is based on the productmolecular weight 421.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21779 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 421.91 |
| Formula | C22H28ClNO5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1779796-27-8 |
| Synonyms | LY-2365109, LY 2365109 |
| SMILES | O=C(O)CN(CCOC1=CC=C(C2=CC=C(OCO3)C3=C2)C=C1C(C)(C)C)C.Cl[H] |
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