LY2811376

目录号: A11776

BACE1 inhibitor

LY2811376 Chemical Structure

CAS NO. 1194044-20-6

LY2811376 is the first orally available non-peptidic BACE1 inhibitor that produces profound Aβ-lowering effects in animals.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 5,000.00
100 mg
¥ 8,500.00
10mM * 1mL in DMSO
¥ 1,170.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

LY2811376 is the first orally available non-peptidic BACE1 inhibitor that produces profound Aβ-lowering effects in animals.
Targets
BACE1
239 nM-249 nM~300 nM(EC50)
In vitro (25°C) DMSO 16 mg/mL (49.94 mM)
Water <1 mg/mL (<1 mM)
Ethanol 64 mg/mL (199.77 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.21 mL 156.05 mL 312.11 mL
0.5 mM 6.24 mL 31.21 mL 62.42 mL
1 mM 3.12 mL 15.61 mL 31.21 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11776
MECHANISM OF ACTION Inhibitor
M. Wt 320.4
Formula C15H14F2N4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1194044-20-6
Synonyms LY 2811376, LY-2811376
SMILES C[C@]1(CCSC(=N1)N)C2=C(C=C(C(=C2)C3=CN=CN=C3)F)F

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 LY2811376 | LY2811376 供应商 | 订购 LY2811376 | LY2811376 价格 | LY2811376 生产商 | 订单 LY2811376 | LY2811376 代理商 | 购买 1194044-20-6| 1194044-20-6 供应商 | 订购 1194044-20-6 | 1194044-20-6 价格 | 1194044-20-6 生产商 | 订单 1194044-20-6 | 1194044-20-6 代理商|buy LY2811376 | LY2811376 Supplier | purchase LY2811376 | LY2811376 cost | LY2811376 manufacturer | order LY2811376 | LY2811376 distributor | buy 1194044-20-6| 1194044-20-6 Supplier | purchase 1194044-20-6 | 1194044-20-6 cost | 1194044-20-6 manufacturer | order 1194044-20-6 | 1194044-20-6 distributor
Rewards