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LY2835219 methanesulfonate

CDK4/6 抑制剂

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产品目录号: A16386


产品名 目录号 价格 数量
LY2835219 methanesulfonate 5mg A16386-5
¥ 500.00
LY2835219 methanesulfonate 10mg A16386-10
¥ 900.00
LY2835219 methanesulfonate 50mg A16386-50
¥ 1,800.00



LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.

LY2835219 methanesulfonate




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Chemical Information

目录号 A16386
Mechanism of action Inhibitor
分子量 602.7
化学分子式 C27H32F2N8.CH4O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1231930-82-7
Synonyms Abemaciclib
SMILES code CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O
化学名称 N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;methanesulfonic acid


LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.59 mL 82.96 mL 165.92mL
0.5 mM 3.32 mL 16.59 mL 33.18 mL
1 mM 1.66 mL 8.3 mL 16.59 mL
5 mM 0.33 mL 1.66 mL 3.32 mL

*The above data is based on the productmolecular weight 602.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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