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LY2857785

目录号: A15823
CDK9 抑制剂
LY2857785 是一种强效且选择性的 CDK9 抑制剂;显著降低 RNAP II CTD 磷酸化,并显著降低 MCL1 蛋白水平,从而在多种白血病和实体瘤细胞系中引发凋亡。
Grouped product items
规格 价格 库存 数量
1mg
¥280.00
现货
2mg
¥420.00
现货
5mg
¥735.00
现货
10mg
¥1,225.00
现货
25mg
¥2,555.00
现货
50mg
¥4,130.00
现货
100mg
¥6,650.00
现货
10mM * 1mL in DMSO
¥840.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.
Targets
Target Value
产品信息
目录号 A15823
分子式 C26H36N6O
分子量 448.6
CAS号 1619903-54-6
SMILES CC(C)C1=C2C=C(C=CC2=NN1C)C3=NC(=NC=C3)NC4CCC(CC4)NC5CCOCC5
其他名称 LY-2857785, LY 2857785
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 22 mg/mL (49.04 mM)
Water Insoluble
Ethanol 40 mg/mL (89.16 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.29 mL 111.46 mL 222.92 mL
0.5 mM 4.46 mL 22.29 mL 44.58 mL
1 mM 2.23 mL 11.15 mL 22.29 mL
5 mM 0.45 mL 2.23 mL 4.46 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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