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M8-B (hydrochloride)

M8-B (hydrochloride)

Name: M8-B (hydrochloride)
SKU: A22607

目录号: A22607

TRPM8 antagonist

M8-B (hydrochloride) Chemical Structure

CAS NO. 883976-12-3

M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).

库存：现货

规格	价格	数量
1 mg	￥ 230.00
2 mg	￥ 390.00
5 mg	￥ 750.00
10 mg	￥ 1,200.00

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生物活性

M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.09 mL	115.47 mL	230.95 mL
0.5 mM	4.62 mL	23.09 mL	46.19 mL
1 mM	2.31 mL	11.55 mL	23.09 mL
5 mM	0.46 mL	2.31 mL	4.62 mL

*The above data is based on the productmolecular weight 433. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A22607
M. Wt	433
Formula	C22H24N2O3S.HCl
Solubility	DMSO
Purity	>98%
Storage	at -20°C 2 years
CAS No.	883976-12-3
Synonyms	M8B (hydrochloride),M8 B (hydrochloride)
SMILES	COC(C=C(CN(C(C1=CC=CS1)=O)CCN)C=C2)=C2OCC3=CC=CC=C3.Cl