MAC glucuronide phenol-linked SN-38

Name: MAC glucuronide phenol-linked SN-38
SKU: A18403
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A18403

DNA topoisomerase I 抑制剂

MAC葡糖醛酸苯酚连接SN-38是一种对pH敏感的内酯型MAC葡糖醛酸苯酚连接SN-38（DNA拓扑异构酶I抑制剂）药物连接体。MAC葡糖醛酸苯酚连接SN-38对L540cy细胞和Ramos细胞具有细胞毒性，其IC50值分别为113和67 ng/mL。

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规格	价格	库存
1mg	¥2,205.00	现货
5mg	¥6,685.00	现货
10mg	¥11,165.00	现货
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Data Sheet

SDS

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生物活性

Discription

MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively.

Targets

Target	Value

产品信息

目录号	A18403
分子式	C50H54N6O20S
分子量	1091.06
CAS号	2246380-69-6
SMILES	O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C(COC(N(COC3=CC=C4N=C5C(CN6C(C(COC([C@@]7(CC)O)=O)=C7C=C65)=O)=C(CC)C4=C3)CCS(=O)(C)=O)=O)C=C2NC(CN(C)C(CCN8C(C=CC8=O)=O)=O)=O)O1)O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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